1. So-young Yeo, Keun-Woo Lee, Dongkwan Shin, Sugyun An, Kwang-Hyun Cho*, Seok-Hyung Kim*. A positive feedback loop bi-stably activates fibroblasts. nature communications 2018 Aug 1;9(1):3016. doi: 10.1038/s41467-018-05274-6. *:corresponding author
2. Hak-Min Lee, Eunmyong Lee, So-young Yeo, Sang Shin, Hyun-Kyu Park, Do-Hyun Nam*, and Seok-Hyung Kim*. Drug repurposing screening identifies bortezomib and panobinostat as drugs targeting cancer associated fibroblasts (CAFs) by synergistic induction of apoptosis. Invest New Drugs. 2018 doi: 10.1007/s10637-017-0547-8. *:corresponding author
3. So-young Yeo, Sang-Yun Ha, Keun-Woo Lee, Yan Cui, Zhao-Ting Yang, Yan-Hua Xuan*, and Seok-Hyung Kim*. Twist1 is highly expressed in cancer-associatedfibroblasts of esophageal squamous cell carcinoma with a prognostic significance. Oncotarget. 2017: 8(39): 65265–65280. *:corresponding author
4. Sung Wook Son*, Seok-Hyung Kim*, Eun-Yi Moon*, Dong-Hoon Kim, Suhkneung Pyo, Sung Hee Um. Prognostic significance and function of the vacuolar H+-ATPase subunit V1E1 in esophageal squamous cell carcinoma. Oncotarget. 2016 7(31) : 49334-49348. *:co-first author
5. Keun-Woo Lee, So-young Yeo, Chang Ohk Sung, and Seok-Hyung Kim*. Twist1 as a key regulator of cancer-associated fibroblasts. Cancer Research 2015 75 : 73-85 *:corresponding author
6. Zhao-Ting Yang, So-Young Yeo, Yong-Xue Yin, Zhen-Hua Lin, Hak-Min Lee, Yan-Hua Xuan, Yan Cui, and Seok-Hyung
Kim*. Tenascin-C,
a Prognostic Determinant of Esophageal Squamous Cell Carcinoma. Plos one 2015 2016:11:e0145807
*:corresponding author
7. H J Kim, S-H
Kim, E J Yu, W-Y Seo and J H Kim. A positive role of DBC1 in
PEA3-mediated progression of estrogen receptor-negative breast cancer.
Oncogene. 2015 34:4500-4508. H J Kim,
S-H Kim equally contributed.
8 So-young Yeo, Sang-Yun Ha, Eun-Ji Eu,
Jeong-Hoon Kim* and Seok-hyung Kim*.
ZNF282 (Zinc finger protein 282), a novel E2F1 co-ativator, promotes esophageal
squamous cell carcinoma. Oncotarget, 2014 in press. *:corresponding author.
9.Su-Yeon Cho, Sang-Yun Ha, Seok-Hyung Kim*. The prognostic significance of Smad3,
Smad4, Smad3 phosphoisoform expression in esophageal squamous cell
carcinoma.Medical oncology 2014 5:12260-12272. *:corresponding author.
10. Keun-Woo Lee, Chang Ohk Sung, and Seok-Hyung Kim*. CD10 expression
is enhanced by Twist1 and associated with poor prognosis in esophageal squamous
cell carcinoma with facilitating tumorigenicity in vitro and in vivo.
International journal of cancer 2015 136:310-321 *:corresponding author
11. Sang-Yun Ha and Seok-Hyung Kim*. The prognostic significance of
cancer-associated fibroblasts in esophageal squamous cell carcinoma. Plos one.
2014:9:e99955 *:corresponding author
12. Keun-Woo Lee, and Seok-Hyung Kim*. Twist1 is essential in maintaining
mesenchymal state and tumor-initiating properties in synovial sarcoma. Cancer
Letters 2014:343:62-73 *:corresponding author
13. Sang-Yun Ha and Seok-Hyung Kim*. Overexpression of matriptase correlates
with poor prognosis in esophageal squamous cell carcinoma. Virchows Archiv.
2014:464:19-27. *:corresponding author
14. Sang-Yun Ha, Ju-Yeon Shin and Seok-Hyung Kim*. Overexpression
of integrin αv
correlates with poor prognosis in colorectal cancer. Journal of clinical
pathology. 2014 67:576-581 *:corresponding author
15. Seok-Hyung
Kim, and Sung-Hee Um. Clinicopathologic significance and function of
mammalian target of rapamycin activation in esophageal squamous cell carcinoma.
Human Pathology. 2013:44:226-236.
16. Chang Ohk Sung, and Seok-Hyung Kim*. Sarcomatoid carcinoma represents a complete
phenotype with various pathways of epithelial mesenchymal transition. Journal
of clinical pathology. 2013 66:601-606 *:corresponding author
17. Seok-Hyung
Kim, and Sung-Hee Um. Prognostic significance and function of
phosphorylated ribosomal protein S6 in esophageal squamous cell carcinoma.
Modern pathology 2013 : 26:327-335
18. Sang-Yun Ha and Seok-Hyung
Kim*. Co-expression of Bmi1 and EZH2 as an independent poor prognostic
factor in esophageal squamous cell carcinoma. Pathology-research and practice.
2012:208:4620469. *:corresponding author
19.
Seok-Hyung Kim, Jung-Hun Kim, and Cherl-Keun Park. The overexpression
of DBC1 in esophageal squamous cell carcinoma correlates with poor prognosis.
Histology and Histopathology. 2012: 27: 49-58
20. Keun-Woo Lee, and Seok-Hyung Kim*. Twist1 causes the transcriptional
repression of claudin-4 with prognostic significance in esophageal cancer.
Biochemical and Biophysical Research Communications 2012: 423 : 454–460 *:corresponding author
21. Chang Ohk Sung, Keun-Woo Lee, Songying Han,
and Seok-Hyung Kim*. Twist1
Is Up-Regulated in Gastric Cancer-Associated Fibroblasts with Poor Clinical
Outcomes. American Journal of Pathology. 2011, 179:1827–1838. *:corresponding author
22. Chang Ohk Sung, Cheol-Keun Park and Seok-Hyung Kim*. Classification
of epithelial–mesenchymal
transition phenotypes in esophageal squamous cell carcinoma is strongly
associated with patient prognosis. Modern Pathology (2011) 24, 1060–1068. *:corresponding author
23. Mi Jeong Kwon*, Seok-Hyung Kim*, Hae Min Jeong, Hun Soon Jung, Sung-Su Kim,,
Jae Eun Lee, Myung Chan Gye, Ozgur Cem Erkin, Sang Seok Koh, Yoon-La Choi,
Cheol Keun Park, and Young Kee Shin. Claudin-4 overexpression is associated
with epigenetic derepression in gastric carcinoma. Laboratory Investigation
(2011) 91, 1652–1667.
*These authors contributed equally to this work.
24. Eun Ji Yu*, Seok-Hyung Kim*, Kyu Heo, Chen-Yin Ou, Michael R. Stallcup
and Jeong Hoon Kim. Reciprocal roles of DBC1 and SIRT1 in regulating estrogen
receptor activity and co-activator synergy. Nucleic Acids Research, 2011, Vol.
39. 6932–6943
*These authors contributed equally to this work.
25. Keun-Woo Lee, Jeong Hoon Kim, Songying Han,
Chang-Ohk Sung, In-Gu Do, Young-hyeh Ko, Sung Hee Um, and Seok-Hyung Kim*. Twist1 Is an Independent Prognostic Factor
of Esophageal Squamous Cell Carcinoma and Associated with Its Epithelial–Mesenchymal Transition. Annals of
surgical oncology. 2011: 19:326-335. *:corresponding author
26. Chang-OK Sung, Song-Yiang Han, Seok-hyung Kim*. Low expression
of claudin-4 is associated with poor prognosis in esophageal squamous cell
carcinoma. Annals of surgical oncology, 2011. 18:273–2810. *:corresponding author
27. Kyung Hee Kim, Jin Man Kim, Yoon-LaChoi,
YoungKeeShin, Ho-changLee, InOck Seong, BumKyung Kim, SeoungWan Chae, Yun-Shin
Chung and Seok-Hyung Kim* .
Expression of Sonic hedgehog signaling molecules in normal, hyperplastic and
carcinomatous endometrium. Pathology International 2009; 59:279–287 *:corresponding author
28. Dongjun Lee, Changwon Park, Ho Lee, Jesse J.
Lugus, Seok Hyung Kim,
Elizabeth Arentson, Yun Shin Chung, Gustavo Gomez, Michael Kyba, Shuo Lin, Ralf
Janknecht, Dae-Sik Lim, and Kyunghee Choi. ER71 Acts Downstream of BMP, Notch,
and Wnt Signaling in Blood and Vessel Progenitor Specification. Cell Stem Cell
2008; 2, 497–507
29. Seok-Hyung
Kim, Seung-Hyun Lee, Yoon-La Choi, Li-Hui Wang, Cheol Keun Park and
Young Kee Shin. Extensive alteration in the expression profiles of TGFB pathway
signaling components and TP53 is observed along the gastric dysplasia-carcinoma
sequence. Histol Histopathol (2008) 23: 1439-1452
30. Kyung-hee Kim, Jin-Man Kim, Yoon-La Choi, Young-Kee Shin,
Seungwan Chae, and Seok-hyung Kim*.
Enhanced CD24 expression in endometrial carcinoma and it sexpression pattern in
normal and hyperplastic endometrium. Histol Histopathol (2009) 24: 309-316
*:corresponding author
31. Jung Hyun Lee*, Seok-Hyung Kim*, Li-Hui Wang, Yoon-La Choi, Young Chul Kim,
Jin Hee Kim, Tae Sung Park, Yun-Chul Hong, and Young Kee Shin. Clinical Sig
nificance of CD99 Down-Regulation in Gastric Adenocarcinoma. Clin Cancer Res
2007;13(9) 2584-2591. (* equal contribution)
32. Li-HuiWang, Seok-Hyung Kim, Jung Hyun Lee, Yoon-La Choi, Young Chul Kim,
Tae Sung Park, Yun-Chul Hong, Chun-FuWu, and Young Kee Shin. Inactivation of
SMAD4 Tumor Suppressor Gene During Gastric Carcinoma Progression. Clin Cancer
Res 2007;13(1): 102-110.
33. Wang LH, Choi YL, Xuan YH, Shin YK, Song YJ,
Youn SJ, Yun HY, Park SM, Kim WJ, Kim HJ, Choi JS and Seok-Hyung Kim* Expression of sonic hedgehog in gast ric
cancer and its related lesions and methylation as its regulating mechanism.
Modern Pathology 2006; 19:675-683. *:corresponding author
34. Xuan YH, Jung HS, Choi YL, Shin YK, Kim KH,
Kim WJ, Seok-Hyung Kim.*
Enhanced expression of hedgehog signaling molecules in squamous cell carcinoma
of uterine cervix and its precursor lesions. Modern Pathology 2006; 19;
1139-1147. *:corresponding author
35. Xuan YH, Choi YL, Shin YK, Ahn GH, Kim KH,
Kim WJ, Seok-Hyung Kim*
Expressi on of TGF-signaling proteins in normal placenta and gestational
trophoblastic disease. histology and histopathology 2007 22:227-234
*:corresponding author